China Tiamulin | 55297-96-6 supplier

Details for Tiamulin

Tiamulin

111Category:

Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents

CAS NO:

55297-96-6

EC NO:

259-581-6

Molecular Formula:

C₃₂H₅₁NO₈S

Molecular Weight:

609.8142

Specification:

EP/USP/Feed Grade

InChI:

InChI=1/C28H47NO4S.C4H4O4/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28;5-3(6)1-2-4(7)8/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t19?,20-,22+,24-,25-,26+,27-,28-;/m0./s1

Packing:

25kg drum

Product description:

TIAMULIN

COMMON NAME: Tiamulin Hydrogen Fumarate

MOLECULAR FORMULAR: C28H47NO4S·C4H4O4

MOLECULAR WEIGHT: 609.82

SPECIFICATION

Items Technical Specifications	Specifications
Appearance	White crystal powder
Identification	IR-spectrum/HPLC retention times
pH	From 3.1 to 4.1
Loss on drying	Not more than 0.5%
Heavy Metals (ppm)	Not more than 10
Fumarate assay	18.6-19.4%
Assay (HPLC)	98.0-102.0%

INDICATION

Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E. coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin.

Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.

Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.

CAUTION

Dont use together with polyether ionophores such as Monesin, Salinomycin etc.

Dont touch with eyes and skin.

STORAGE

Keep in dry ,cool places; Seal the bag after use.

PACKAGE

25 Kg drum

Uses:

Antibiotic for Animal Use

Synonyms:

Tiamuline Hydrogen Fumarate;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;DENAGARD;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu;Tiamulin Fumarate;(4R,5S,6S,8R,9aS,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);(3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);

Molecular Structure:

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