Vitamin K1

Pharmaceuticals and Biochemicals/Vitamin, amino acids and coenzymes

Chemical namesPhytomenadione, phylloquinone,Phytonadione, 2-methyl-3-phytyl-1, 4-naphthoquinone

CAS No. 8480-0EINECS No. 201-564-2

DescriptionFree-flowing light yellow powder that consists of fine spherical particles.

CompositionThe spherical particles contain vitamin K1 oil dissolved in droplets of 1-2μm embedded in a matrix of gum Arabic(E414), sucrose and coated with modified starch. The product contains t-butylhydroxytoluene(BHT,E 321)and DL-α-tocopherol(E 307). as an antioxidant.

SolubilityThe product can be dispersed in cold water to form a stable milky emulsion.

SpecificationAssay: min. 1% vitamin K1Loss on drying: max.5%(4 hours at 105℃)

MonographsNo monographs exist for this product

Particle-size distribution 100% smaller than 425μm(40 mesh USP)mean particle size: 150μm(100 mesh USP)

Bulk densityApprox.0.6g/ml

Stabilization/StabilityWhen the product is stored in the unopened original container at room temperature(max. 25℃) The product is stable for at least 36 months.

Packaging1,5,25kg fibreboard box with AL-PE laminated liner, heat-sealedStorageThe product should be stored in the tightly close containers at room temperature(about 25℃). It is essential to protect the product from light.

ApplicationsPharmaceutical preparations:For the manufacture of solid products with vitamin K1 as the sole active ingredient, as well as multivitamin and mineral preparations, e.g. tables, sugar-coated tablets, instant drink granules, effervescent tablets, hard gelatin capsules.Food products:For the fortification of baby food and children抯 food, dietetic foods, instant drink powders, dried milk, and for vitamin mixtures for the food industry. Dry vitamin K1 1% can also be used in multivitamin fruit juices and confectionery, e.g. multivitamin sweets. Very suitable for the manufacture of hypoallergenic food s ,as the product contains no protein.

Note Dry vitamin K1 1%GFP must be handled in accordance with Safety Data Sheet.