111Category: | Intermediates |
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CAS NO: | 56-69-9 | |||||||||||||||||||||||||||||||||||||
EC NO: | 200-284-8 | |||||||||||||||||||||||||||||||||||||
Molecular Formula: | C11H12N2O3 | |||||||||||||||||||||||||||||||||||||
Molecular Weight: | 220.2246 | |||||||||||||||||||||||||||||||||||||
Specification: | ||||||||||||||||||||||||||||||||||||||
InChI: | InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1 | |||||||||||||||||||||||||||||||||||||
Product description: Product Name:5-HTP(L-5-Hydroxytryptophan) Botanical Name: Griffonia simplicifolia Part Used: Seed Main Active Ingredient: 5-HTP(L-5-Hydroxytryptophan) ---------------------------------------------------------------------------------------------------------------------- Specification: 20%-99 % 5-HTP ---------------------------------------------------------------------------------------------------------------------- Active Ingredient:5-HTP CAS No.: 4350-09-8 Mol. Formula: C11H12N2O3 Mol. Weight: 220.23 Structural formula: ---------------------------------------------------------------------------------------------------------------------- Description: 5-HTP is sold over-the-counter in the United States, the United Kingdom, and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. 5HTP in supplement form is typically sold in 50 mg or 100 mg gelatin or vegetarian capsules. It is usually sourced from the seeds of Griffonia simplicifolia.5HTP has been studied and shown to be of benefit in the following conditions: primary fibromyalgia syndrome, Friedreich's ataxia, depression, anxiety, binge eating associated with obesity, and insomnia. There is no statistically significant difference between 5HTP and placebo in treating chronic headaches (primary or otherwise).A 2001 meta analysis found that of 108 studies on 5HTP published between 1966 and 2000, only two met the authors' quality standards for inclusion. The two studies that were deemed of sufficient quality did not deal with 5HTP exclusively, instead combining results for 5HTP and tryptophan, so the results may not be completely applicable for 5HTP alone. While the combined analysis of the two 5HTP and tryptophan studies showed significant effectiveness over placebo in treating depression, the authors state that overall "the evidence was of insufficient quality to be conclusive". They also state that "because alternative antidepressants exist which have been proven to be effective and safe, the clinical usefulness of 5HTP and tryptophan is limited at present. ----------------------------------------------------------------------------------------------------------------------
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Synonyms: | 5-hydroxy-dl-tryptophan crystalline;5-Hydroxy-DL-tryptophan;5-hydroxytrytophan;DL-2-Amino-3-[3-(5-hydroxyindole)]propionic acid;2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;5-hydroxytryptophan;H-Trp(5-OH)-OH;5-HTP;5-hydroxy-D-tryptophan; | |||||||||||||||||||||||||||||||||||||
Molecular Structure: |