Details for Naringin
Naringin
111Category: Intermediates
CAS NO: 10236-47-2 EC NO: 233-566-4 Molecular Formula: C27H32O14 Molecular Weight: 580.5346 Specification: InChI: InChI=1/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27-/m0/s1 Product description:
Product Name: Naringin
Botanical Name: Citrus paradisi Macf
Part Used: Skin
Main Active Ingredient: Naringin
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Specification:
98% Naringin
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Active Ingredient: Naringin
CAS No.:10236-47-2
Mol. Formula: C27H32O14
Mol. Weight: 580.54
Structural formula:
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Description:
Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice
the bitter taste. It is metabolized to the flavanone naringenin in humans. Both
naringenin and hesperetin, which are the aglycones of naringin and hesperidin,
occur naturally in citrus fruits. Naringin exerts a variety of pharmacological effects
such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition
of selected drug metabolizing cytochrome P450 enzymes, including CYP3A4 and
CYP1A2, which may result in drug
interactions in vivo. Ingestion of naringin and related flavonoids can also affect the
intestinal absorption of certain drugs, leading to either an increase or decrease in
circulating drug levels.
Main Function:
1.Anti-inflammatory, anti-viral, anti-mutation, anti-carcinogen.
2.Hypotensive activity, function as urogastrone, alleviating pain.
3.Tranquilizing, lowering blood viscosity , reduce the emerge of the thrombus.
4.Improving partial microcirculation of nourishment, preventing and curing
cardiovascular disease
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Specification Sheet
Items
Specification
Naringin
≥98%
Appearance
Fine grey white powder
Odor
Characteristic
Taste
Characteristic
Particle size
NLT 95% pass 80 mesh
Loss on drying
≤5%
Heavy metals
<10ppm
Irradiation
Irradiation Free
GMO
GMO Free
As
<1ppm
Pb
<3ppm
Total Plate Count
<10000cfu/g
Yeast & Mold
<300cfu/g
E.Coli
Negative
Salmonella
Negative
Physical Standard
CP2010
Chemical&Microorganism
StandardUSP34
Synonyms: 2-O-(6-D¨¦soxy-alpha-L-mannopyranosyl)-b¨ºta-D-glucopyranoside de 5-hydroxy-2-(4-hydroxyph¨¦nyl)-4-oxo-3,4-dihydro-2H-chrom¨¦n-7-yle;4',5,7-trihydroxyflavanone 7-rhamnoglucoside;4H-1-benzopyran-4-one, 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-;5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside;5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside;7-[[2-O-(6-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-on;7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one;7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxym¨¦thyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-m¨¦thylt¨¦trahydro-2H-pyran-2-yl]oxy}t¨¦trahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-hydroxyph¨¦nyl)-2,3-dihydro-4H-chrom¨¦n-4-one;Aurantiin;(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside;(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-D-galactopyranosyl)-beta-D-glucopyranoside;(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-D-glucopyranoside;7-(2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone;Naringoside; Molecular Structure: 
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